To be clear, this does not mean for Christians to live against homosexuals through demonization and hatred as many have. Nor does it mean to have an “us versus them” mentality with the LGBT community. Rather, to live against the world means to live in opposition to the "spirit of the age;" that ever-compelling, always subtle spirit which seeks to blur the lines and buy our souls in the process. Christ’s Kingdom is in opposition to that spirit—His light eradicates its darkness. Therefore there can be no conflict of interest in His followers. Either you serve Jesus or you serve the "spirit of the age." Following one means war with the other.
A decision to live contra mundum will not be fun. You will not be promoted or celebrated. Like Athanasius, opposition to the world’s principles will always be met with hostility and derision. Maybe even your grandchildren will spurn you legacy.
Does it matter? It seems like a small cross to bear in response to our Savior, who for our sake was made "to be sin who knew no sin, so that in him we might become the righteousness of God."
Only let us hear His call and follow.